DR. STEPHEN FORMAN AND CHRISTINE BROWN, PH.D
The Cellular Immunotherapy Center at City of Hope was first established as a small research lab in the late 1990s with the dream of developing novel cellular therapies that specifically target tumor cells. Since these early days, through the leadership of Drs. Stephen Forman and Christine Brown, and the wonderful support of City of Hope Leadership, the research has grown into the translational therapy program known today as the Cellular Immunotherapy Center.
One of the most promising areas of cancer research and treatment right now is known as immunotherapy, in which a patient’s own immune system is enlisted in the fight against cancer. City of Hope has made Cellular Immunotherapy a central component of their groundbreaking research and clinical trials currently underway.
Through the Cellular Immunotherapy Center, City of Hope continues to be at the forefront of a powerful form of immunotherapy known as chimeric antigen receptor (CAR) T cell therapy. Using this approach, immune cells are taken from a patient’s bloodstream, reprogrammed to recognize and attack a specific protein found in cancer cells, then reintroduced into the patient’s system, where they get to work destroying targeted tumor cells.